Cannabidiol as a Potential Treatment for Anxiety Disorders.
The review everyone quotes says the human CBD evidence is acute-dosing only — has anything since then actually tested taking it every day for an anxiety disorder?
Weak or heavily disputed. Treat as a question, not an answer. how we score evidence
Caveat on this rating: The low score reflects study design, not disputed findings: this is a narrative review with no systematic search, no pooled estimate, and no readable funding statement, so it carries little independent evidentiary weight even though its cautious conclusion has held up.
One cannabidiol product is FDA-approved: Epidiolex (plant-derived purified CBD oral solution), indicated for seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex in patients 1 year and older.
The most-cited review of CBD for anxiety concluded that animal evidence is strong but that human evidence is limited to single acute doses, with very few studies in people who actually have an anxiety disorder and essentially none on chronic dosing. Ten years on, that gap has still not been filled by adequately powered trials.
Worth asking
The review everyone quotes says the human CBD evidence is acute-dosing only — has anything since then actually tested taking it every day for an anxiety disorder?
Source
Cannabidiol as a Potential Treatment for Anxiety Disorders. — Blessing EM, Steenkamp MM, Manzanares J, Marmar CR. (2015)
Reputable peer-reviewed journal
Read the source: https://doi.org/10.1007/s13311-015-0387-1
DOI: 10.1007/s13311-015-0387-1
How this was scored
- Study design
- Narrative review
- Funding
- Funding not disclosed
- Published in
- Reputable peer-reviewed journal
- Sample size
- not recorded
- Preregistered
- No
- Conflicts disclosed
- No
- Independent of proponent
- not recorded
- Retracted
- No
Read the full scoring rubric, including what it can't tell you.
Published August 19, 2026.
Where we put this study in context
Questions
How strong is the evidence behind this?
Resolv rates this source "contested". Weak or heavily disputed. Treat as a question, not an answer. It scores 33 out of 100 on our published rubric. One caveat travels with that badge: The low score reflects study design, not disputed findings: this is a narrative review with no systematic search, no pooled estimate, and no readable funding statement, so it carries little independent evidentiary weight even though its cautious conclusion has held up. The score is calculated from recorded facts about the source — study design, funding, publication venue, sample size, preregistration — not typed in by an editor.
What is the source for this?
Cannabidiol as a Potential Treatment for Anxiety Disorders. — Blessing EM, Steenkamp MM, Manzanares J, Marmar CR. (2015). Published in: Reputable peer-reviewed journal. DOI: 10.1007/s13311-015-0387-1. The full source is linked on this page so you can read it yourself.
Who paid for this research, and does that matter?
Study design: Narrative review. Funding: Funding not disclosed. Independence from the proponent is not recorded. Industry sponsorship is one of the most reliably measured biases in medicine, which is why funding carries real weight in the score rather than sitting in a footnote.
Is cannabidiol, cbd, hemp extract, cbd oil, epidiolex, full-spectrum hemp FDA approved for this use?
No. Its current status is: Not FDA-evaluated for this use. One cannabidiol product is FDA-approved: Epidiolex (plant-derived purified CBD oral solution), indicated for seizures associated with Lennox-Gastaut syndrome, Dravet syndrome, or tuberous sclerosis complex in patients 1 year and older.
Is this medical advice?
This is information to bring to your prescriber, not medical advice and not a reason to change anything on your own. Nothing here is an instruction to stop or reduce a medication. If you are in crisis, call or text 988.
This is information to bring to your prescriber, not medical advice and not a reason to change anything on your own. Nothing here is an instruction to stop or reduce a medication. If you are in crisis, call or text 988.